Glucosamine Supplements May Speed Memory Loss from Alzheimer's New Research Suggests

[GreatGazoo]

(THE CONVERSATION) People with Alzheimer’s disease who took the common supplement glucosamine were 25% more likely to die within five years than those who didn’t. That’s the key finding of a new study that my colleagues and I published in the journal Nature Metabolism.
...
We found that glucosamine also affected people in the earliest stage of memory loss, a condition called mild cognitive impairment. People in this early stage of dementia who were taking glucosamine were 25% more likely to progress to full Alzheimer’s.
...
We then conducted experiments in mice engineered to have Alzheimer’s-like symptoms to identify the potential mechanism behind how glucosamine may affect the brain. We found that blocking the enzyme that makes sugars like glucosamine improved dementia symptoms in mice. In contrast, feeding those same mice glucosamine made memory loss worse. Healthy mice given the same supplement showed no effect.

https://www.seattlepi.com/news/glucosamine-supplements-may-speed-memory-loss-a22298160

[erronis]

1. This is a serious finding. These types of supplements are very poorly tested.

And of course glucosamine (and chondroitin) are heavily marketed and consumed by older people.

Folks - please be skeptical about "cures" that friends or social influencers tell you about. At least run them by some legit health-care provider for their opinion.

[mopinko]

3. they make enough money. they cd test this crap. but

they’d prove a lot of it is bs, then where wd they b?

[mucifer]

2. It's not a double blind study. Seems more of a preliminary study

[GreatGazoo]

4. yes. correlation plus a proposed mechanism nt