So what happens to the 25th amendment if the cabinet has been fired?

[mackdaddy]

12. I don't think there is a high likelihood of it being invoked, even though it should be.

But, there have been stories of Trump being concerned it could be. This could be part of his decisions to start cleaning house.

I don't think he could directly fire VP Vance, but getting rid of at least some other Cabinet level people certainly throws a legal question that does not seem to be directly addressed in the amendment text.

The other thing is although this is a far out thing to actually have happen, Trump is seriously ill mentally and physically and is doing things that are literally destroying the world economy and ordering daily war crimes. Who knows what kind of crap he will pull next? Too bad the republicans in the house will just not vote for impeachment to end this.