Glucosamine Supplements May Speed Memory Loss from Alzheimer's New Research Suggests [View all]
(THE CONVERSATION) People with Alzheimers disease who took the common supplement glucosamine were 25% more likely to die within five years than those who didnt. Thats the key finding of a new study that my colleagues and I published in the journal Nature Metabolism.
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We found that glucosamine also affected people in the earliest stage of memory loss, a condition called mild cognitive impairment. People in this early stage of dementia who were taking glucosamine were 25% more likely to progress to full Alzheimers.
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We then conducted experiments in mice engineered to have Alzheimers-like symptoms to identify the potential mechanism behind how glucosamine may affect the brain. We found that blocking the enzyme that makes sugars like glucosamine improved dementia symptoms in mice. In contrast, feeding those same mice glucosamine made memory loss worse. Healthy mice given the same supplement showed no effect.
https://www.seattlepi.com/news/glucosamine-supplements-may-speed-memory-loss-a22298160